Sweet and Low is generally considered safe for human consumption by major food safety authorities like the Food and Drug Administration when used in moderation. The primary sweetening ingredient in Sweet and Low is saccharin, which has been thoroughly studied for decades without definitive evidence of harming humans at normal dietary levels. Some people prefer to avoid artificial sweeteners due to personal health preferences or potential digestive sensitivities. Consulting a healthcare provider can help determine if artificial sweeteners fit your dietary goals.